Beauty and Skin Care

Skin Care and Beauty :Bristol drug extends survival in deadly skin cancer

admin — Mon, 21 Jun 2010 07:27:31 +0000

Bristol-Myers Squibb Co’s experimental skin cancer drug ipilimumab added an average of four months to the lives of patients with advanced melanoma, U.S. researchers said on Saturday, representing a major advance in a disease littered with drug failures.
Melanoma is one of the

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Bristol-Myers Squibb Co’s experimental skin cancer drug ipilimumab added an average of four months to the lives of patients with advanced melanoma, U.S. researchers said on Saturday, representing a major advance in a disease littered with drug failures.

Melanoma is one of the deadliest cancers and can quickly spread from the skin to internal organs, such as the brain.

“Once it metastasizes, the average survival is six to nine months and we really had no effective treatments for patients who have had prior treatment for melanoma,” said Dr. Steven O’Day, one of the study’s lead investigators.

In the 676-patient study, patients who got the drug survived for an average of 10 months, compared with just over six months if they just got a vaccine treatment called gp100, investigators found.

The four-month difference represented a 67 percent increase in survival, O’Day told reporters at the American Society of Clinical Oncology meeting in Chicago.

For some patients, the benefit was lasting, with more than 20 percent of those who took the drug still alive after two years, and some still alive even four years after treatment.

“I think this a breakthrough for the field of metastatic melanoma that has had a lot of negative Phase 3 trials in the last decade. It’s impacting survival, which is the gold standard in cancer clinical trials,” O’Day, director of the melanoma program at the Angeles Clinic and Research Institute in Santa Monica, California, said in a telephone interview.

Ipilimumab helps to activate the immune system to fight the cancer. Doctors give it to patients in a 90-minute infusion every three weeks for a total of four doses.

All patients in the trial had previous treatment for melanoma before getting either an experimental cancer vaccine called GP-100, ipilimumab, or a combination of the two.

Both groups that got the Bristol drug had a statistically significant improvement in overall survival compared with those who just got the vaccine, researchers said.

In the two ipilimumab arms, the drug cut the risk of death from melanoma by 32 percent to 34 percent compared with the vaccine alone.

“If you look at one-year and two-year survival, there was a near doubling of benefit with ipilimumab,” O’Day said.

One-year survival was seen in 25 percent of the vaccine patients, compared with 44 percent on the combination and 46 percent for ipilimumab alone.

After two years, 14 percent of vaccine patients were alive versus 22 percent and 24 percent in the Bristol drug arms.

In the 20 percent to 30 percent of patients for whom the drug really works, survival “tends to be months and years, not weeks and months like chemotherapy,” O’Day said.

HOPES FOR SPEEDY APPROVAL

He said a genetic biomarker test was needed to determine just which patients were most likely to benefit from the drug.

Since the drug enlists the help of the immune system, it does have some serious side effects.

About two-thirds of patients on ipilimumab had some form of immune-related side effects compared with one-third on vaccine, researchers said.

Most were mild and completely reversible, but about 10 to 14 percent of patients had more severe side effects, such as colitis, that required treatment with steroids or immunosuppressive drugs, O’Day explained.

Some 2 percent to 3 percent of patients on ipilimumab died from the treatment because of colon perforation or other severe immune system side effects.

Doctors would have to closely monitor patient reaction, O’Day said, but he added the side effects could be managed.

O’Day believes ipilimumab may also work in other types of cancer.

Leerink Swann analyst Seamus Fernandez forecasts ipilimumab sales of 5 million in 2016 with an approval for metastatic melanoma.

But some doctors worry that patients will start asking for the drug and will not be able to get it.

“This is not an FDA-approved drug,” said Dr. Lynn Schuchter, a skin cancer specialist at the University of Pennsylvania, who was not involved in the study.

“Patients are going to have a lot of hope and want this drug and it’s not going to be on their doctors’ shelves.”

She said it may be possible for patients to get the drug through melanoma centers of excellence either in a clinical trial or through a so-called compassionate use protocol.

O’Day is counting on a speedy approval.

“We’re hopeful that this (data) is the beginning of what will be a rapid regulatory processing to try to get this drug on the market and access to more patients with melanoma,” O’Day said.

(Reporting by Bill Berkrot and Julie Steenhuysen; Editing by Peter Cooney)

Technorati Tags: cancer, ipilimumab, melanoma, skin cancer, skin cancer drug

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Beauty Skin Care :State-of-the-Art Laser Systems

admin — Mon, 21 Jun 2010 07:27:30 +0000

Ask us about skin rejuvenation… Ask us about this exciting new option for hair removal… Ask us about this effective new option for the treatment of leg veins.

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Ask us about skin rejuvenation… Ask us about this exciting new option for hair removal… Ask us about this effective new option for the treatment of leg veins.

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Beauty Skin Care :3 Easy Steps To Rid Your Skin Of Acne!

admin — Mon, 21 Jun 2010 07:27:30 +0000

For a large number of teenagers and young adults, achieving a clear skin is a very difficult task. If you are an acne sufferer, there is no need to worry. You can get a smooth skin by acquiring the right information and with proper guidance you would be amazed at the texture of your

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For a large number of teenagers and young adults, achieving a clear skin is a very difficult task. If you are an acne sufferer, there is no need to worry. You can get a smooth skin by acquiring the right information and with proper guidance you would be amazed at the texture of your skin. In this article you would discover how you can get rid of your acne pimples quickly and efficiently. If you are having troubles with acne breakouts then I urge you to follow these easy yet effective steps to getting a better skin.Step 1You should begin a cleaning regimen that you can use to clean the tiny pores on your skin every day. Asides cleaning your pores, the topical product that you use should be able to fight the acne causing bacteria that are situated on the surface of the skin. These products act to clean deep into your skin pores every time you use them and they are effective in the treatment of acne.They are a few acne products that have this ability to both cleanse your skin and fight acne causing bacteria. I will let you know more about these products later on. Step 2Diet is very important! You must start eating healthier foods!! Stop eating all those junk foods and start eating plenty of fruits and vegetables. Avoid foods that are prepared using a lot of vegetable oil. This is because the oil can get into your skin pores and clog them up. This only leads to more acne pimples appearing on your skin. Also, start drinking plenty of water. This is very important in keeping your body and skin healthy. Drinking an adequate amount of water every day helps to flush out harmful toxins out of your body each day. Step 3Use a double combination acne treatment to combat your acne pimples. What I mean is that you should use a treatment that combats your acne both from the inside of your body and the surface of your skin. There are a few acne products that fight acne this way. A topical product would fight the acne causing bacteria on the surface of the skin, while a supplement would attack the root causes of acne, one of which is hormonal imbalances.There is no point struggling to get rid of acne when you can easily get it off your skin and begin living your life acne free. Stop wasting your time and your hard earned money on acne treatments that just don’t work. It’s not worth it! A double combination acne treatment would get rid of your acne pimples quickly and efficiently.

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Beauty Skin Care :Rating of Clinique Liquid Facial Soap

admin — Sun, 13 Jun 2010 07:30:40 +0000

Clinique Liquid Facial SoapRating: * * * *Price: USClinique provides 3 skin-typed formulas for its liquid facial soap: Extra mild, Mild, and Oily. Extra mild is for dry skin, Mild is for normal to dry skin, and Oily is for normal to oily skin.I have dry and combination skin (oily

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Clinique Liquid Facial SoapRating: * * * *Price: USClinique provides 3 skin-typed formulas for its liquid facial soap: Extra mild, Mild, and Oily. Extra mild is for dry skin, Mild is for normal to dry skin, and Oily is for normal to oily skin.I have dry and combination skin (oily in the t-zone areas) so I am using the “Mild”. I have been using this product for at least a year now and it works really well. I think the most remarkable thing for this product is that it thoroughly cleanse your skin without making your skin dry.Have you used Clinique Liquid Facial Soap?What's your rating of Clinique Liquid Facial Soap?

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Beauty and Skin Care :Rating of SANA’s Ho-Jun-Ki toner

admin — Sun, 13 Jun 2010 07:30:40 +0000

SANA’s Ho-Jun-Ki toner (化妝水)Rating: * * * * *Price: US.99I live right next to a Japanese supermarket. They have all kinds of skin care and beauty products. This moisture lotion is one of the “treasures” I found in the supermarket.This moisture lotion focuses on tightening

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SANA’s Ho-Jun-Ki toner (化妝水)Rating: * * * * *Price: US.99I live right next to a Japanese supermarket. They have all kinds of skin care and beauty products. This moisture lotion is one of the “treasures” I found in the supermarket.This moisture lotion focuses on tightening pores while moisturizing your skin. It contains royal jelly which some sources says keeps skin young. I learned that applying moisture lotion after cleansing your face is a very important step. The result is especially good when you swipe it on with a cotton. The reason being that it helps get rid of the soap residue left behind from the cleansing process. Also, since the moisture lotion is in liquid form, it is very easy for your skin to absorb after cleansing.I have used this product for almost 2 months now. I think the result is very good. Every time after I applied the product, my skin looks radiant, smooth, and supple. My pore does look less apparent as well after using the product. I highly recommend it.Have you used SANA’s Ho-Jun-Ki toner?What's your rating of SANA's Ho-Jun-Ki toner?

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Skin Care and Beauty :Pond’s flawless white day cream

admin — Sun, 13 Jun 2010 07:30:40 +0000

Pond’s flawless white visible lightening daily UV creamRating: * *Price: ~HK0This next product i’m going to rate is pond’s flawless white visible lightening daily UV cream. I have been using the Pond’s double white line in the pass year. The result was pretty good. It was cheap

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Pond’s flawless white visible lightening daily UV creamRating: * *Price: ~HK0This next product i’m going to rate is pond’s flawless white visible lightening daily UV cream. I have been using the Pond’s double white line in the pass year. The result was pretty good. It was cheap as well. I usually ask my sister in hk to buy it for me and then ship it over to US. However, my sister told me that Pond’s is ending their double white line and this Pond’s flawless white line should work the same as the Pond’s double white cream. I tried this new line for a few weeks now and I do not like it very much. The cream is too greasy and it wasn’t easy to be absorbed. I usually applies it in the morning. At the end of the day, my face gets really oily. I feel that it is so greasy that my pores are starting to clog. The only thing I like about this cream is that it has SPF PA ++ which serves like sun block. I will have to switch to another day cream soon. I am thinking of trying the Shiseido White Lucent Brightening Protective Moisturizer. Have you used Pond’s flawless white visible lightening daily UV cream?What's your rating of Pond's flawless white visible lightening daily UV cream?

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Skin Care and Beauty :Rating of Pond’s flawless white re-brightening night treatment

admin — Sun, 13 Jun 2010 07:30:40 +0000

Pond’s flawless white re-brightening night treatmentRating: * * *Price: ~ HK0This is the night cream for the Pond’s flawless white line. I gave this product a higher rating because I feel that it worked well whitening your skin. I’ve been using this product for a few nights

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Pond’s flawless white re-brightening night treatmentRating: * * *Price: ~ HK0This is the night cream for the Pond’s flawless white line. I gave this product a higher rating because I feel that it worked well whitening your skin. I’ve been using this product for a few nights now and my skin looks paler in the morning when I wake up. So I think it works quite well whitening your skin and it gives instant results. However, it has the same problem as the Pond’s flawless white visible lightening daily UV cream. The formula is too greasy for me and it was not easy to be absorbed. It doesn’t work well as a moisturizer in my opinion.Have you used Pond’s flawless white re-brightening night treatment? What's your rating of Pond's flawless white re-brightning night treatment?

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Skin Care and Beauty :Rating of Origins “Drink Up” 10 Minute Mask

admin — Sun, 13 Jun 2010 07:30:40 +0000

Origins “Drink Up” 10 Minute MaskRating: * * Price: US This mask contains Algae extracts and apricot kernel oil. I used it for a while and did not see much result from it. After using the mask, I did not feel my skin being more hydrated and bascially didn’t see much difference

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Origins “Drink Up” 10 Minute MaskRating: * * Price: US This mask contains Algae extracts and apricot kernel oil. I used it for a while and did not see much result from it. After using the mask, I did not feel my skin being more hydrated and bascially didn’t see much difference before I applied the mask and after. In terms of finding a good moisturizing/hydrating mask, I highly recommend Kracie’s super moist mask and Body Shop’s Vitamin E Sink-In Moisture Mask. I have been using these two masks for a while and it worked really well. I will rate them in my up coming posts. Have you used Origins “Drink Up” 10 Minute Mask?What's your rating of Origins Drink Up 10 Minute Mask?

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Skin Care and Beauty :Rating of Body Shop’s Vitamin E Moisture Mask

admin — Sun, 13 Jun 2010 07:30:40 +0000

Body Shop’s Vitamin E Moisture MaskRating: * * * *Price: US.50This moisturizing mask contains vitamin E. Quoting Body Shop’s description of this product: ‘Vitamin E is a natural antioxidant that neutralizes free radicals, moisturizes and helps to protect against premature aging.

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Body Shop’s Vitamin E Moisture MaskRating: * * * *Price: US.50
This moisturizing mask contains vitamin E. Quoting Body Shop’s description of this product: ‘Vitamin E is a natural antioxidant that neutralizes free radicals, moisturizes and helps to protect against premature aging. Wheat germ oil and rice bran oil, both rich natural sources of vitamin E, moisturize, nourish and help to condition skin.’
I have been using this mask for more than a year now and I think the result is really good. After a 15 minutes mask, I feel my skin is more supple and hydrated. The mask feels very light so it doesn’t clog pores. I highly recommend this mask.Have you used Body Shop’s Vitamin E Moisture Mask?What’s your rating of Body Shop’s Vitamin E Moisture Mask?

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Skin Care :Rating of Clinique’s Superbalm Lip Treatment

admin — Sun, 13 Jun 2010 07:30:40 +0000

Clinique’s Superbalm Lip TreatmentRating: * * * * *Price: US.50This is by far the best lip treatment I have ever used. I especially like to apply the lip treatment before I go to bed so when I wake up the next morning my lips are deeply moisturized. This product also helps eliminate

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Clinique’s Superbalm Lip TreatmentRating: * * * * *Price: US.50This is by far the best lip treatment I have ever used. I especially like to apply the lip treatment before I go to bed so when I wake up the next morning my lips are deeply moisturized. This product also helps eliminate the wrinkles on my lips. Giving it a fresh, pumped, young look. Also giving it a rosy pink color. I highly recommend this product.Have you used Clinique’s Superbalm Lip Treatment?What's your rating of Clinique's Superbalm Lip Treatment?

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